Entrée Capital has unveiled $300 million in funds to invest in early-stage cryptocurrencies and Web3 infrastructure, a move that underscores the accelerating institutional appetite for blockchain systems that seamlessly interface with modern technology stacks.
The fund will target investments from pre-seed to Series A, supporting founders in building the foundational layers for mainstream Web3 adoption, the company said in an email on Thursday. Targets include artificial intelligence (AI) agents capable of autonomously managing assets within crypto policy frameworks, as well as decentralized physical infrastructure (DePIN) networks and blockchain protocols that use token incentives to coordinate, finance, and operate real-world infrastructure.
Entrée says its long history in fintech and crypto — including early bets on Stripe, Rapid, Mesh and Web3 creators like Gen Labs and Breez — positions it to support founders at the intersection of regulated finance and decentralized networks.
Institutional investors pay close attention to both Artificial intelligence agents and Demin Because they serve as crypto-native counterparts to two of today’s fastest-growing technology pillars: artificial intelligence and cloud computing.
AI agents promise autonomous asset management governed by crypto policy frameworks, while DePIN networks extend the cloud model by coordinating and financing physical infrastructure. Together, they provide a path to secure, automated and highly scalable digital and physical facilities, in line with enterprises’ broader push towards next-generation infrastructure.
